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Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.

Two mutants defective in herpes simplex virus-encoded ribonucleotide reductase activity exhibited the novel phenotype of hypersensitivity to acyclovir, aphidicolin, and to a lesser extent, phosphonoacetic acid. These results have implications for acyclovir resistance and the development of drugs tha...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Coen, D M, Goldstein, D J, Weller, S K
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1395
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