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Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers
We characterized antigen-specific CD4(+) T cells in six patients with treatment-resistant Lyme arthritis, using an HLA-DRB1*0401 major histocompatibility complex (MHC) class II tetramer covalently loaded with OspA(164–175), an immunodominant epitope of Borrelia burgdorferi. Direct analysis of OspA-t...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17217/ https://ncbi.nlm.nih.gov/pubmed/11005833 |
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