Inhibitory effects of quinolones on pro- and eucaryotic DNA topoisomerases I and II.

As a means of gaining information on the selectivity of quinolone antibacterial agents, we examined their effect on four topoisomerases, topoisomerases I and II purified from Escherichia coli and calf thymus. The inhibition of supercoiling and relaxation activities was monitored by using the classic...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Moreau, N J, Robaux, H, Baron, L, Tabary, X
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1963290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.10.1955
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