Inhibitory effects of quinolones on pro- and eucaryotic DNA topoisomerases I and II.
As a means of gaining information on the selectivity of quinolone antibacterial agents, we examined their effect on four topoisomerases, topoisomerases I and II purified from Escherichia coli and calf thymus. The inhibition of supercoiling and relaxation activities was monitored by using the classic...
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| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1963290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.10.1955 |
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