Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents.

Norfloxacin, ofloxacin, and other new quinolones, which are antagonists of the enzyme DNA gyrase, rapidly kill bacteria by largely unknown mechanisms. Earlier, we isolated, after mutagenesis, Escherichia coli DS1, which exhibited reduced killing by quinolones. We evaluated the killing of DS1 and sev...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Wolfson, J S, Hooper, D C, McHugh, G L, Bozza, M A, Swartz, M N
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1990
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1963289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.10.1938
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