Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli.
In Escherichia coli the frequency of spontaneous single-step mutation to high levels of resistance to the newer 4-quinolone agent norfloxacin was confirmed to be over 300-fold lower than that to the older agent nalidixic acid. Serial passage on incremental concentrations of drug was necessary to pro...
Guardado en:
| Publicado en: | Antimicrob Agents Chemother |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1986
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.4.639 |
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