Hypersusceptibility of the Pseudomonas aeruginosa nfxB Mutant to β-Lactams Due to Reduced Expression of the AmpC β-Lactamase

The Pseudomonas aeruginosa nfxB mutant lacking mexAB-oprM showed hypersusceptibility to 9 out of 24 β-lactams tested. This hypersusceptibility was found for the nfxB mutant lacking mexAB-oprM-mexXY (N108) but not for the nfxB mutant lacking both mexAB-oprM-mexXY and ampC. The level of the AmpC β-lac...

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Bibliografski detalji
Glavni autori: Masuda, Nobuhisa, Sakagawa, Eiko, Ohya, Satoshi, Gotoh, Naomasa, Nishino, Takeshi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90457/
https://ncbi.nlm.nih.gov/pubmed/11257048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1284-1286.2001
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