Hypersusceptibility of the Pseudomonas aeruginosa nfxB Mutant to β-Lactams Due to Reduced Expression of the AmpC β-Lactamase

The Pseudomonas aeruginosa nfxB mutant lacking mexAB-oprM showed hypersusceptibility to 9 out of 24 β-lactams tested. This hypersusceptibility was found for the nfxB mutant lacking mexAB-oprM-mexXY (N108) but not for the nfxB mutant lacking both mexAB-oprM-mexXY and ampC. The level of the AmpC β-lac...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Masuda, Nobuhisa, Sakagawa, Eiko, Ohya, Satoshi, Gotoh, Naomasa, Nishino, Takeshi
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Mechanisms of Resistance
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90457/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11257048/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.4.1284-1286.2001
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