Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli.

In Escherichia coli the frequency of spontaneous single-step mutation to high levels of resistance to the newer 4-quinolone agent norfloxacin was confirmed to be over 300-fold lower than that to the older agent nalidixic acid. Serial passage on incremental concentrations of drug was necessary to pro...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Hooper, D C, Wolfson, J S, Souza, K S, Tung, C, McHugh, G L, Swartz, M N
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.4.639
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