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Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.

DL-alpha-Difluoromethylornithine is an enzyme-activated inhibitor of ornithine decarboxylase and an antagonist of polyamine metabolism that has been successful in clinical trials against West African sleeping sickness caused by Trypanosoma brucei gambiense. Its potential for use against the more vir...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Bacchi, C J, Nathan, H C, Livingston, T, Valladares, G, Saric, M, Sayer, P D, Njogu, A R, Clarkson, A B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1990
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1183
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