Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.

DL-alpha-Difluoromethylornithine is an enzyme-activated inhibitor of ornithine decarboxylase and an antagonist of polyamine metabolism that has been successful in clinical trials against West African sleeping sickness caused by Trypanosoma brucei gambiense. Its potential for use against the more vir...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Bacchi, C J, Nathan, H C, Livingston, T, Valladares, G, Saric, M, Sayer, P D, Njogu, A R, Clarkson, A B
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1990
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1183
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