Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.

DL-alpha-Difluoromethylornithine is an enzyme-activated inhibitor of ornithine decarboxylase and an antagonist of polyamine metabolism that has been successful in clinical trials against West African sleeping sickness caused by Trypanosoma brucei gambiense. Its potential for use against the more vir...

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Bibliografski detalji
Glavni autori: Bacchi, C J, Nathan, H C, Livingston, T, Valladares, G, Saric, M, Sayer, P D, Njogu, A R, Clarkson, A B
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC171781/
https://ncbi.nlm.nih.gov/pubmed/2118325
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