Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.

DL-alpha-Difluoromethylornithine is an enzyme-activated inhibitor of ornithine decarboxylase and an antagonist of polyamine metabolism that has been successful in clinical trials against West African sleeping sickness caused by Trypanosoma brucei gambiense. Its potential for use against the more vir...

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Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Bacchi, C J, Nathan, H C, Livingston, T, Valladares, G, Saric, M, Sayer, P D, Njogu, A R, Clarkson, A B
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1183
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