Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo.

Nascent polyoma DNA molecules were isolated after pulse-labeling of infected murine 3T6 cells with [3H]thymidine. The extent of digestion of these DNA molecules by spleen exonuclease was increased by exposure to alkali or RNase, suggesting that ribonucleotides were present at or near the 5' terminal...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Närkhammar-Meuth, M, Kowalski, J, Denhardt, D T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6268811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.39.1.21-30.1981
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