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Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo.

Nascent polyoma DNA molecules were isolated after pulse-labeling of infected murine 3T6 cells with [3H]thymidine. The extent of digestion of these DNA molecules by spleen exonuclease was increased by exposure to alkali or RNase, suggesting that ribonucleotides were present at or near the 5' ter...

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Detalhes bibliográficos
Main Authors: Närkhammar-Meuth, M, Kowalski, J, Denhardt, D T
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171261/
https://ncbi.nlm.nih.gov/pubmed/6268811
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