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Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo.

Nascent polyoma DNA molecules were isolated after pulse-labeling of infected murine 3T6 cells with [3H]thymidine. The extent of digestion of these DNA molecules by spleen exonuclease was increased by exposure to alkali or RNase, suggesting that ribonucleotides were present at or near the 5' terminal...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Närkhammar-Meuth, M, Kowalski, J, Denhardt, D T
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1981
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171261/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6268811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.39.1.21-30.1981
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