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A four-way junction accelerates hairpin ribozyme folding via a discrete intermediate

The natural form of the hairpin ribozyme comprises two major structural elements: a four-way RNA junction and two internal loops carried by adjacent arms of the junction. The ribozyme folds into its active conformation by an intimate association between the loops, and the efficiency of this process...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Tan, Elliot, Wilson, Timothy J., Nahas, Michelle K., Clegg, Robert M., Lilley, David M. J., Ha, Taekjip
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2003
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC170914/
https://ncbi.nlm.nih.gov/pubmed/12883002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233536100
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