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Dissection of the ion-induced folding of the hammerhead ribozyme using (19)F NMR

We have used (19)F NMR to analyze the metal ion-induced folding of the hammerhead ribozyme by selective incorporation of 5fluorouridine. We have studied the chemical shift and linewidths of (19)F resonances of 5-fluorouridine at the 4 and 7 positions in the ribozyme core as a function of added Mg(2+...

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Detalhes bibliográficos
Main Authors: Hammann, Christian, Norman, David G., Lilley, David M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33242/
https://ncbi.nlm.nih.gov/pubmed/11331743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091097498
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