Dissection of the ion-induced folding of the hammerhead ribozyme using (19)F NMR

We have used (19)F NMR to analyze the metal ion-induced folding of the hammerhead ribozyme by selective incorporation of 5fluorouridine. We have studied the chemical shift and linewidths of (19)F resonances of 5-fluorouridine at the 4 and 7 positions in the ribozyme core as a function of added Mg(2+...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Hammann, Christian, Norman, David G., Lilley, David M. J.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.091097498
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