A four-way junction accelerates hairpin ribozyme folding via a discrete intermediate
The natural form of the hairpin ribozyme comprises two major structural elements: a four-way RNA junction and two internal loops carried by adjacent arms of the junction. The ribozyme folds into its active conformation by an intimate association between the loops, and the efficiency of this process...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12883002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1233536100 |
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