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Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway

During the biosynthesis of the vancomycin-class antibiotic chloroeremomycin, TDP-epi-vancosaminyltransferase GtfA catalyzes the attachment of 4-epi-vancosamine from a TDP donor to the β-OHTyr-6 of the aglycone cosubstrate. Glycosyltransferases from this pathway are potential tools for the combinator...

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Detalhes bibliográficos
Main Authors: Mulichak, Anne M., Losey, Heather C., Lu, Wei, Wawrzak, Zdzislaw, Walsh, Christopher T., Garavito, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC170902/
https://ncbi.nlm.nih.gov/pubmed/12874381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233577100
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