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Crystal structure of a tetrameric GDP-d-mannose 4,6-dehydratase from a bacterial GDP-d-rhamnose biosynthetic pathway

d-Rhamnose is a rare 6-deoxy monosaccharide primarily found in the lipopolysaccharide of pathogenic bacteria, where it is involved in host–bacterium interactions and the establishment of infection. The biosynthesis of d-rhamnose proceeds through the conversion of GDP-d-mannose by GDP-d-mannose 4,6-d...

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Autores principales: Webb, Nicole A., Mulichak, Anne M., Lam, Joseph S., Rocchetta, Heather L., Garavito, R. Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286695/
https://ncbi.nlm.nih.gov/pubmed/14739333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03393904
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