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Mutation of GDP-Mannose-4,6-Dehydratase in Colorectal Cancer Metastasis
Fucosylation is a crucial oligosaccharide modification in cancer. The known function of fucosylation in cancer is to mediate metastasis through selectin ligand-dependent processes. Previously, we found complete loss of fucosylation in the colon cancer cell line HCT116 due to a mutation in the GDP-fu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726606/ https://ncbi.nlm.nih.gov/pubmed/23922970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070298 |
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