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Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin
Chloroeremomycin, a vancomycin family glycopeptide antibiotic has three sugars, one d-glucose and two l-4-epi-vancosamines, attached to the crosslinked heptapeptide backbone by three glycosyltransferases, GtfA, -B, and -C. Prior efforts have revealed that GtfB and -C in tandem build an epivancosamin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384757/ https://ncbi.nlm.nih.gov/pubmed/15070728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400277101 |
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