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Role of extracellular subdomains of p185(c-neu) and the epidermal growth factor receptor in ligand-independent association and transactivation
We investigated the assembly and activation of the epidermal growth factor receptor (EGFR)–p185(c-neu) heterodimer by using a sequential immunoprecipitation methodology. Using this approach we detected heterodimers and also higher-ordered oligomeric complexes. Phosphorylated EGFR–p185(c-neu) heterod...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170899/ https://ncbi.nlm.nih.gov/pubmed/12867596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633546100 |
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