Загрузка...
Long-distance conformational changes in a protein engineered by modulated sequence duplication
There are few, if any, known instances in which a biological signal is transmitted via a large conformational change through the body of a protein. We describe here a mutant of T4 lysozyme that was engineered to permit structural change at a distance. The design uses a tandem sequence repeat that ma...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170894/ https://ncbi.nlm.nih.gov/pubmed/12869697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633549100 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|