Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding
To test a different approach to understanding the relationship between the sequence of part of a protein and its conformation in the overall folded structure, the amino acid sequence corresponding to an α-helix of T4 lysozyme was duplicated in tandem. The presence of such a sequence repeat provides...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6078 |
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