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Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding

To test a different approach to understanding the relationship between the sequence of part of a protein and its conformation in the overall folded structure, the amino acid sequence corresponding to an α-helix of T4 lysozyme was duplicated in tandem. The presence of such a sequence repeat provides...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Sagermann, Martin, Baase, Walter A., Matthews, Brian W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26838/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6078
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