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Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA
We report a strategy for the reagentless transduction of DNA hybridization into a readily detectable electrochemical signal by means of a conformational change analogous to the optical molecular beacon approach. The strategy involves an electroactive, ferrocene-tagged DNA stem–loop structure that se...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC170884/ https://ncbi.nlm.nih.gov/pubmed/12867594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633515100 |
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