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Optimization of a Reusable, DNA Pseudoknot-Based Electrochemical Sensor for Sequence-Specific DNA Detection in Blood Serum

We describe in detail a new electrochemical DNA (E-DNA) sensing platform based on target-induced conformation changes in an electrode-bound DNA pseudoknot. The pseudoknot, a DNA structure containing two stem-loops in which the first stem’s loop forms part of the second stem, is modified with a methy...

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Detalhes bibliográficos
Main Authors: Cash, Kevin J., Heeger, Alan J., Plaxco, Kevin W., Xiao, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861039/
https://ncbi.nlm.nih.gov/pubmed/19093760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac802011d
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