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Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

The deposition of proteins onto newly spliced mRNAs has far reaching consequences for their subsequent metabolism. We affinity-purified spliced human mRNPs under physiological conditions from HeLa nuclear extract and present the first comprehensive inventory of their protein composition as determine...

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Detalhes bibliográficos
Main Authors: Merz, Christian, Urlaub, Henning, Will, Cindy L., Lührmann, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1705747/
https://ncbi.nlm.nih.gov/pubmed/17095540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.336807
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