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Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

The deposition of proteins onto newly spliced mRNAs has far reaching consequences for their subsequent metabolism. We affinity-purified spliced human mRNPs under physiological conditions from HeLa nuclear extract and present the first comprehensive inventory of their protein composition as determine...

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Библиографические подробности
Главные авторы: Merz, Christian, Urlaub, Henning, Will, Cindy L., Lührmann, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1705747/
https://ncbi.nlm.nih.gov/pubmed/17095540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.336807
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