Insertion of the T3 DNA polymerase thioredoxin binding domain enhances the processivity and fidelity of Taq DNA polymerase

Insertion of the T3 DNA polymerase thioredoxin binding domain (TBD) into the distantly related thermostable Taq DNA polymerase at an analogous position in the thumb domain, converts the Taq DNA polymerase from a low processive to a highly processive enzyme. Processivity is dependent on the presence...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Davidson, John F., Fox, Richard, Harris, Dawn D., Lyons-Abbott, Sally, Loeb, Lawrence A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 2003
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg667
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