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A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization

The three-dimensional structure of bacteriophage T7 DNA polymerase reveals the presence of a loop of 4 aa (residues 401–404) within the DNA-binding groove; this loop is not present in other members of the DNA polymerase I family. A genetically altered T7 DNA polymerase, T7 polΔ401–404, lacking these...

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Autors principals: Chowdhury, Kajal, Tabor, Stanley, Richardson, Charles C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18787/
https://ncbi.nlm.nih.gov/pubmed/11050188
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