A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization
The three-dimensional structure of bacteriophage T7 DNA polymerase reveals the presence of a loop of 4 aa (residues 401–404) within the DNA-binding groove; this loop is not present in other members of the DNA polymerase I family. A genetically altered T7 DNA polymerase, T7 polΔ401–404, lacking these...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230448397 |
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