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GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin
Insulin slows GLUT4 internalization by an unknown mechanism. Here we show that in unstimulated adipocytes, GLUT4 is internalized by two mechanisms. Approximately 80% of GLUT4 is internalized by a mechanism that is sensitive to the cholesterol-aggregating drug nystatin, and is independent of AP-2 cla...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698906/ https://ncbi.nlm.nih.gov/pubmed/17139247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601462 |
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