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Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

Insulin stimulates glucose uptake by regulating translocation of the GLUT4 glucose transporter from intracellular compartments to the plasma membrane. In the absence of insulin GLUT4 is actively sequestered away from the general endosomes into GLUT4-specialized compartments, thereby controlling the...

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書誌詳細
主要な著者: Jordens, Ingrid, Molle, Dorothee, Xiong, Wenyong, Keller, Susanna R., McGraw, Timothy E.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883947/
https://ncbi.nlm.nih.gov/pubmed/20410133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-02-0158
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