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ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
The phosphatidyl inositol 3-kinase-like kinases (PIKKs), ataxia-telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR) regulate parallel damage response signalling pathways. ATM is reported to be activated by DNA double-strand breaks (DSBs), whereas ATR is recruited to single-stranded regions...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698893/ https://ncbi.nlm.nih.gov/pubmed/17124492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601446 |
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