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Huntingtin inhibits caspase-3 activation
Huntington's disease results from a mutation in the HD gene encoding for the protein huntingtin. The function of huntingtin, although beginning to be elucidated, remains largely unclear. To probe the prosurvival function of huntingtin, we modulate levels of wild-type huntingtin in a number of c...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698892/ https://ncbi.nlm.nih.gov/pubmed/17124493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601445 |
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