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Transcriptional Regulation of the Huntingtin Gene
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide expansion in the HTT gene, which encodes for an abnormal polyglutamine tract in the huntingtin protein (HTT). This review examines the known mechanisms of HTT gene regulation. We discuss HTT e...
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| Pubblicato in: | J Huntingtons Dis |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
IOS Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294578/ https://ncbi.nlm.nih.gov/pubmed/30452421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180331 |
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