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The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
TRPV4 is a widely expressed member of the transient receptor potential (TRP) family that facilitates Ca(2+) entry into nonexcitable cells. TRPV4 is activated by several stimuli, but it is largely unknown how the activity of this channel is terminated. Here, we show that ubiquitination represents an...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Nature Publishing Group
2006
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698878/ https://ncbi.nlm.nih.gov/pubmed/17110928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601429 |
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