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The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels

TRPV4 is a widely expressed member of the transient receptor potential (TRP) family that facilitates Ca(2+) entry into nonexcitable cells. TRPV4 is activated by several stimuli, but it is largely unknown how the activity of this channel is terminated. Here, we show that ubiquitination represents an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wegierski, Tomasz, Hill, Kerstin, Schaefer, Michael, Walz, Gerd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698878/
https://ncbi.nlm.nih.gov/pubmed/17110928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601429
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