Cortical Neuronal and Glial Pathology in TgTau(P301L) Transgenic Mice : Neuronal Degeneration, Memory Disturbance, and Phenotypic Variation

Recapitulation of tau pathologies in an animal model has been a long-standing goal in neurodegenerative disease research. We generated transgenic (TgTau(P301L)) mice expressing a frontotemporal dementia with parkinsonism linked to chromosome 17 (FTPD-17) mutation within the longest form of tau (2N,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Murakami, Tetsuro, Paitel, Erwan, Kawarabayashi, Takeshi, Ikeda, Masaki, Chishti, M. Azhar, Janus, Christopher, Matsubara, Etsuro, Sasaki, Atsushi, Kawarai, Toshitaka, Phinney, Amie L., Harigaya, Yasuo, Horne, Patrick, Egashira, Nobuaki, Mishima, Kenichi, Hanna, Amanda, Yang, Jing, Iwasaki, Katsunori, Takahashi, Mitsuo, Fujiwara, Michihiro, Ishiguro, Koichi, Bergeron, Catherine, Carlson, George A., Abe, Koji, Westaway, David, St. George-Hyslop, Peter, Shoji, Mikio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698843/
https://ncbi.nlm.nih.gov/pubmed/17003492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051250
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky