Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice

Missense mutations of the tau gene cause autosomal dominant frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), an illness characterized by progressive personality changes, dementia, and parkinsonism. There is prominent frontotemporal lobe atrophy of the brain accompanied by...

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Main Authors: Ikeda, Masaki, Shoji†, Mikio, Kawarai, Toshitaka, Kawarabayashi, Takeshi, Matsubara, Etsuro, Murakami, Tetsuro, Sasaki, Atsushi, Tomidokoro, Yasushi, Ikarashi, Yasushi, Kuribara, Hisashi, Ishiguro, Koichi, Hasegawa, Masato, Yen, Shu-Hui, Chishti, M. Azhar, Harigaya, Yasuo, Abe, Koji, Okamoto, Koichi, St. George-Hyslop, Peter, Westaway, David
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2005
Teme:
Original Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602315/
https://ncbi.nlm.nih.gov/pubmed/15681835
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