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Transthyretin Accelerates Vascular Aβ Deposition in a Mouse Model of Alzheimer's Disease
Transthyretin (TTR) binds amyloid‐β (Aβ) and prevents Aβ fibril formation in vitro. It was reported that the lack of neurodegeneration in a transgenic mouse model of Alzheimer's disease (AD) (Tg2576 mouse) was associated with increased TTR level in the hippocampus, and that chronic infusion of...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094645/ https://ncbi.nlm.nih.gov/pubmed/18429966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00166.x |
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