Disease Modifying Therapies for Alzheimer's Disease Targeting Aβ Oligomers: Implications for Therapeutic Mechanisms

Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO an...

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Detalhes bibliográficos
Main Authors: Matsubara, Etsuro, Takamura, Ayumi, Okamoto, Yasuhide, Oono, Hideto, Nakata, Takashi, Wakasaya, Yasuhito, Kawarabayashi, Takeshi, Shoji, Mikio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770037/
https://ncbi.nlm.nih.gov/pubmed/24063020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/984041
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