Transthyretin Accelerates Vascular Aβ Deposition in a Mouse Model of Alzheimer's Disease

Transthyretin (TTR) binds amyloid‐β (Aβ) and prevents Aβ fibril formation in vitro. It was reported that the lack of neurodegeneration in a transgenic mouse model of Alzheimer's disease (AD) (Tg2576 mouse) was associated with increased TTR level in the hippocampus, and that chronic infusion of...

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Publicado en:Brain Pathol
Autores principales: Wati, Henny, Kawarabayashi, Takeshi, Matsubara, Etsuro, Kasai, Ayumi, Hirasawa, Takae, Kubota, Takeo, Harigaya, Yasuo, Shoji, Mikio, Maeda, Shuichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2008
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094645/
https://ncbi.nlm.nih.gov/pubmed/18429966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00166.x
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