Novel mRNA Targets for Tristetraprolin (TTP) Identified by Global Analysis of Stabilized Transcripts in TTP-Deficient Fibroblasts

Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived from them showed that TTP could bind to certain AU-rich elements in mRNAs, leading to increases in the rates of mRNA...

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Bibliografiske detaljer
Main Authors: Lai, Wi S., Parker, Joel S., Grissom, Sherry F., Stumpo, Deborah J., Blackshear, Perry J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698545/
https://ncbi.nlm.nih.gov/pubmed/17030620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00945-06
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