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Dependence of Cisplatin-Induced Cell Death In Vitro and In Vivo on Cyclin-Dependent Kinase 2

Cisplatin is one of the most effective chemotherapeutics, but its usefulness is limited by its toxicity to normal tissues, including cells of the kidney proximal tubule. The purpose of these studies was to determine the mechanism of cisplatin cytotoxicity. It was shown in vivo that cisplatin adminis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Price, Peter M., Yu, Fang, Kaldis, Philipp, Aleem, Eiman, Nowak, Grażyna, Safirstein, Robert L., Megyesi, Judit
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698291/
https://ncbi.nlm.nih.gov/pubmed/16914540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006020162
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