Single Nucleotide Polymorphism in the Cytolethal Distending Toxin B Gene Confers Heterogeneity in the Cytotoxicity of Actinobacillus actinomycetemcomitans

Clinical Actinobacillus actinomycetemcomitans produces cytolethal distending toxin (CDT) with titers ranging from 10(2) to 10(8) U/mg. Single nucleotide polymorphism analysis of the cdt gene in clinical isolates identified a variation of a single amino acid at residue 281 of CdtB, which significantl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nishikubo, Shuichi, Ohara, Masaru, Ikura, Masae, Katayanagi, Katsuo, Fujiwara, Tamaki, Komatsuzawa, Hitoshi, Kurihara, Hidemi, Sugai, Motoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698065/
https://ncbi.nlm.nih.gov/pubmed/16982823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02063-05
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky