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Role of Pairwise Interactions between M1 and M2 Domains of the Nicotinic Receptor in Channel Gating
The adult form of the nicotinic acetylcholine receptor (AChR) consists of five subunits (α(2)βɛδ), each having four transmembrane domains (M1–M4). The atomic model of the nicotinic acetylcholine receptor shows that the pore-lining M2 domains make no extensive contacts with the rest of the transmembr...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1697868/ https://ncbi.nlm.nih.gov/pubmed/17028140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088757 |
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