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Kinetic Analysis of Amyloid Protofibril Dissociation and Volumetric Properties of the Transition State

We present here the first detailed kinetic analysis of the dissociation reaction of amyloid protofibrils by utilizing pressure as an accelerator of the reaction. The experiment is carried out on an excessively diluted typical protofibril solution formed from an intrinsically denatured disulfide-defi...

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Bibliografiske detaljer
Main Authors: Abdul Latif, Abdul Raziq, Kono, Ryohei, Tachibana, Hideki, Akasaka, Kazuyuki
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1697859/
https://ncbi.nlm.nih.gov/pubmed/16997869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088120
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