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Kinetic Analysis of Amyloid Protofibril Dissociation and Volumetric Properties of the Transition State

We present here the first detailed kinetic analysis of the dissociation reaction of amyloid protofibrils by utilizing pressure as an accelerator of the reaction. The experiment is carried out on an excessively diluted typical protofibril solution formed from an intrinsically denatured disulfide-defi...

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Detalhes bibliográficos
Main Authors: Abdul Latif, Abdul Raziq, Kono, Ryohei, Tachibana, Hideki, Akasaka, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1697859/
https://ncbi.nlm.nih.gov/pubmed/16997869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088120
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